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The registry shows the Phase 2 obesity trial of eloralintide reached primary completion

Phase II P1 Primary public evidence Trial registry record

ClinicalTrials.gov lists 30 May 2025 as the primary completion date of NCT06230523, the Phase 2 placebo-controlled trial of eloralintide in 263 adults with obesity or overweight. The record gives 14 August 2025 as the study completion date and has a results section.

263

Participants, as recorded in the registry

48 weeks

Primary endpoint time point: percent change in body weight

Background and context

Where this trial sits

The record lists this study as one that ran under the chronic weight management master protocol (NCT06143956). It compares eloralintide with placebo, double-blind, and the primary endpoint is percent change in body weight from baseline to week 48. Participation lasted about 64 weeks.

Who took part

Adults aged 18 to 75 met the master protocol criteria, a BMI of at least 30 or at least 27 with a weight-related condition. People with diabetes, a history of pancreatitis, a history of bradyarrhythmia or sinus bradycardia, or a recent heart attack, stroke, unstable angina or heart failure hospitalisation were excluded. All listed sites are in the United States.

Where the results are

The record has a results section on the registry, which this entry does not restate. The peer-reviewed paper and the sponsor announcement have their own entries in this section. The study completed on 14 August 2025.

Trial record: ClinicalTrials.gov NCT06230523, read on 2026-10-15. Registered plans can change.

Source

ClinicalTrials.gov record NCT06230523, read on 2 October 2026

P1 Primary public evidence Trial registry record. An official trial registration. A registration shows that a study exists; it does not show that the compound works.

Figures checked against this source on . How this site grades evidence

Related trial: NCT06230523, Phase II, 48-week obesity trial (trial record on this site)